The best cartridge and bullet to drop a bison

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Bison are North America’s largest land mammals, bigger than Africa’s notorious Cape buffalo. They are powerful, unpredictable and potentially dangerous, so your cartridge and bullet selection—and shot placement—are critical. A .30-06 cartridge with a heavy bullet is a sensible minimum, but .30- and .338-calibre magnums are better choices. Even larger calibres, such as the .375 and .416 families, are not out of place on these immense animals.

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To hit the vitals, aim at the bison’s lower third

Whatever cartridge you select, only use premium, controlled-expansion bullets to ensure deep penetration through a bison’s thick muscle and bone. The hump and massive shoulder often mislead hunters, so aim at the lower third of the body to ensure a heart and lung shot. That will kill a bison, but not quickly, so it’s a good idea to keep shooting until the animal is down.